Enterotoxins and toxic-shock syndrome toxin-1 in non-enteric staphylococcal disease
نویسندگان
چکیده
منابع مشابه
Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever.
We investigated the involvement of the recently described staphylococcal enterotoxins G and I in toxic shock syndrome. We reexamined Staphylococcus aureus strains isolated from patients with menstrual and nonmenstrual toxic shock syndrome (nine cases) or staphylococcal scarlet fever (three cases). These strains were selected because they produced none of the toxins known to be involved in these...
متن کاملStaphylococcal toxic-shock-syndrome-toxin-1 as a risk factor for disease relapse in Wegener's granulomatosis.
OBJECTIVES Nasal carriage of Staphylococcus aureus constitutes a risk factor for disease exacerbation in Wegener's granulomatosis (WG). We hypothesized that staphylococcal superantigens (SAg) are a determinant of S. aureus-related risk for disease relapse in WG. METHODS In a retrospective longitudinal cohort study in 62 WG patients, we investigated the presence of the staphylococcal SAg genes...
متن کاملStaphylococcal toxic shock syndrome.
A 28 year old male presented with fever, tachycardia, generalized lymphadenopathy and diffuse rash over the body. He failed to respond to intravenous antibiotics and developed cardiogenic shock, multiple organ failure and died within six hours after hospitalization. Staphylococcus aureus colonies were revealed on blood culture.
متن کاملThe Staphylococcal Toxic Shock Syndrome
Toxic shock syndrome toxin 1 (TSST1)t is a 22-kD exotoxin produced by most strains ofStaphylococcus aureus isolated from patients with toxic shock syndrome (TSS) (1) . TSST1 is a potent activator of monocytes and T cells . It acts on monocytes to induce the synthesis of IL-1 and TNF (2-4) . TSSTl also triggers T cell activation and proliferation (5), as well as the production of large amounts o...
متن کاملEpithelial Proinflammatory Response and Curcumin-Mediated Protection from Staphylococcal Toxic Shock Syndrome Toxin-1
Staphylococcus aureus initiates infections and produces virulence factors, including superantigens (SAgs), at mucosal surfaces. The SAg, Toxic Shock Syndrome Toxin-1 (TSST-1) induces cytokine secretion from epithelial cells, antigen presenting cells (APCs) and T lymphocytes, and causes toxic shock syndrome (TSS). This study investigated the mechanism of TSST-1-induced secretion of proinflammato...
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ژورنال
عنوان ژورنال: Epidemiology and Infection
سال: 1993
ISSN: 0950-2688,1469-4409
DOI: 10.1017/s0950268800050901